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Remark: Barbiturates may perhaps raise adverse effects, together with respiratory melancholy, produced by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates raise metabolism and reduce blood concentrations of TCAs.pentobarbital will lower the extent or outcome of meloxicam by impacting hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Unknown.
pentobarbital will decrease the level or effect of alfuzosin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.
Keep track of Intently (one)pentobarbital will lower the extent or effect of tadalafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or effect of carbamazepine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Insignificant (1)pentobarbital will minimize the extent or effect of paclitaxel protein certain by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
Monoamine oxidase inhibitors (MAOI) may possibly inhibit barbiturate metabolism and prolong barbiturate effects; observe intently
pentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral type of both equally agents. Small/Significance Unidentified.
pentobarbital will reduce the level or effect of colchicine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will minimize the extent or impact of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the extent pentobarbital online or outcome of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or outcome of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or outcome of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or result of ramelteon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.